What is BPC-157?
BPC-157 (Body Protective Compound 157) is a synthetic pentadecapeptide derived from a sequence identified in human gastric juice. It is one of the most widely cited research peptides in the soft-tissue and gastric-repair literature.
Preclinical work has explored BPC-157 across models of tendon, ligament, and gastrointestinal injury, with mechanisms broadly tied to angiogenesis, nitric-oxide signaling, and growth-factor expression.
How it's studied — mechanism
BPC-157's reported activity in pre-clinical literature includes:
- Modulation of angiogenesis and capillary network formation
- Up-regulation of the nitric-oxide (NO) pathway and VEGF expression
- Enhanced fibroblast migration and growth-factor receptor expression
- Cytoprotective effects in gastric and intestinal mucosa models
Amino acid sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-ValPublished research
The following primary sources are provided to support qualified-researcher review. Inclusion is for reference only and does not constitute medical advice or therapeutic claim.